ViroBiome Skin First

ViroBiome™ Skin First

A new generation of cosmetic actives for anti-aging, radiance, UV protection and microbiome balance

Overview

ViroBiome™ Skin First is a next-generation biomimetic active complex combining
• a furin-inhibiting biofilm derived from the plant resin Protium heptaphyllum, creating an invisible biological shield that limits the activation of viral and photo-inflammatory proteases. This action protects the skin from UV-induced stress by reducing IL-6 production, lipid oxidation, and collagen degradation.
• Rapeseed ceramides that rebuild intercellular cohesion, stimulate collagen synthesis, and restore the lipid barrier for firmer, smoother, and more resilient skin.
• Rapeseed peptides that enhance cellular vitality, reduce wrinkles, and even skin tone through telomerase activation and tyrosinase inhibition.

Together, these three patented actives form a living, self-regulating protection and regeneration system for the skin.

Mechanism of Action

Furin inhibition and natural UV protection
The triterpenes of Protium heptaphyllum inhibit furin-like proteases involved in UV-induced inflammatory and oxidative cascades. This reduces the formation of IL-6 and MMP-1, prevents collagen breakdown, and provides a biological defense equivalent to a natural sunscreen effect. It also helps maintain microbiome diversity and resilience.

Barrier reinforcement
Rapeseed ceramides restore the lipid lamellae of the epidermis, reducing transepidermal water loss and improving the skin’s structural integrity.

Cellular renewal and brightening
Low-molecular-weight rapeseed peptides activate telomerase in keratinocytes, support collagen renewal, and inhibit melanogenesis in melanocytes for an even, luminous complexion.

Proven Benefits

• Firmer, smoother, and visibly younger skin
• Enhanced radiance and even tone
• Biological UV and oxidative stress protection via furin inhibition
• Reinforced skin barrier and long-lasting hydration
• Balanced, protected, and resilient skin microbiome

All active ingredients are dermatologically tested, clinically validated, and fully compliant with EU Cosmetic Regulation (EC) No. 1223/2009.

Why Consumers Will Love It

• Intelligent skin protection: a living biological shield that prevents UV and pollution damage before it occurs.
• Plant-based innovation: powered by rapeseed and Amazonian resin actives obtained through green chemistry.
• Scientific transparency: efficacy proven through ex vivo and clinical studies (IL-6 reduction, telomerase activation, ZAG stimulation).
• Microbiome respect: formulated for natural balance and skin comfort.
• Clean, sustainable, and high-performance beauty: a perfect match for the growing demand for bio-intelligent, microbiome-safe skincare.

Advantages of an Exclusive Perpetual License

Global exclusivity on a patented One Health technology that connects skin protection and cellular longevity.

Scientific differentiation through the first cosmetic ingredient providing UV protection via furin inhibition.

Strong and durable IP: validated European patents with international extensions in progress.

Cross-segment potential: applicable in skincare, suncare, anti-aging, dermocosmetics, and clean beauty lines.

Ready-to-use formulation base: Uption supplies the active concentrate in customizable dilution levels.

Premium communication opportunity: unique narrative around “living protection” and “bio-intelligent beauty.”

ESG alignment: biodegradable, non-toxic, non-animal tested, and derived from upcycled agricultural materials.

Associated Patents

Furin-inhibiting resin (Protium heptaphyllum)
Patent EP4138793B1
https://worldwide.espacenet.com/patent/search/family/075438820/publication/EP4138793A1?q=pn%3DEP4138793

Rapeseed peptides
Patent EP4134135A1
https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=fr_EP&FT=D&date=20230215&CC=EP&NR=4134135A1&KC=A1

Rapeseed ceramides
Patent EP4151203A1
https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=fr_EP&FT=D&date=20230322&CC=EP&NR=4151203A1&KC=A1