ViroBiome Cera

ViroBiome™ Cera

Plant Based Rapeseed Ceramide Complex

Rapeseed Ceramides Together With Their Associated Membrane Phospholipids

Lipid Barrier Reinforcement & Microbiome Compatible Resilience

For urban exposure, climate stress and aging related lipid fragility

Executive Overview

ViroBiome™ CERA is a patented lipophilic plant derived complex obtained from Brassica napus, also known as rapeseed meal, through a controlled ethanol extraction process.

It is designed as a structural lipid module for next generation augmented hygiene, exposed biological interfaces and functional nonwoven systems.

Patent status

Patented technology

Plant based rapeseed ceramide complex

European patent granted

The patent describes a rapeseed meal extract obtained through a process including rapeseed pressing, recovery of the meal, grinding, extraction with 96° ethanol, filtration, solvent evaporation and recovery of the extract .

ViroBiome™ CERA provides a concentrated botanical lipid fraction containing:

• rapeseed ceramides together with their associated membrane phospholipids
• C8 to C24 fatty amides
• natural gamma tocopherols
• natural alpha tocopherols
• antioxidant polyphenols
• residual plant proteins from rapeseed meal

The patent specifies that the extract may contain 0.5% to 1.25%, preferably 0.9%, of compounds selected from ceramides and C8 C24 fatty amides, as well as preferred contents of gamma tocopherols and alpha tocopherols .

CERA is positioned as a lipid barrier reinforcement ingredient designed to support structural resilience, surface comfort and microbiome compatible balance in exposed biological interfaces.

It is not positioned as a pharmaceutical active, disinfectant, biocide or medicinal treatment.

Why CERA Matters Now

Biological interfaces are under increasing pressure.

Urban exposure, demographic aging and climate warming are weakening the natural lipid architecture of skin and exposed surfaces.

Conventional skincare often focuses on hydration.

ViroBiome™ CERA introduces a deeper functional logic.

Rebuild. Reinforce. Preserve.

It supports the lipid organization of exposed interfaces and helps maintain barrier resilience in high contact, pollution exposed and aging sensitive environments.

Macro Context

Urbanization

High density environments increase:

• particulate and pollutant exposure
• oxidative stress
• repeated surface contact
• friction and cleansing cycles
• daily pressure on skin and mucosal adjacent interfaces

These factors may contribute to surface discomfort, lipid imbalance and barrier fatigue.

Population Aging

Aging tissues may present:

• reduced lipid cohesion
• lower ceramide availability
• weaker barrier integrity
• increased dehydration pressure
• slower recovery after friction or exposure
• greater sensitivity to environmental stress

As skin ages, barrier fragility becomes structural rather than occasional.

Climate Warming

Climate warming adds a third systemic pressure on exposed biological interfaces.

Rising temperatures, heat waves, pollution peaks, wildfire particles, longer pollen seasons and increased aeroallergen exposure may intensify daily stress on skin, mucosa adjacent zones and fragile epithelial surfaces.

Climate warming can contribute to:

• increased heat stress on exposed tissues
• higher oxidative pressure from pollution and wildfire particles
• longer and more intense allergen exposure
• greater skin sensitivity during extreme weather events
• increased dehydration pressure on the epidermal barrier
• more frequent interaction between pollution, humidity, heat and biological surface imbalance

Together, urbanization, aging and climate warming create a structural need for technologies that reinforce the lipid resilience of exposed interfaces.

What Is ViroBiome™ CERA?

ViroBiome™ CERA is a plant derived lipid complex obtained by valorizing rapeseed meal, a by product of rapeseed oil production.

The extract is obtained through a controlled process involving:

• rapeseed sourcing
• pressing and recovery of rapeseed meal
• grinding to an average particle size below or equal to 5 mm
• extraction using 96° ethanol
• filtration
• solvent evaporation
• recovery of the lipophilic extract

The patent indicates that after ethanol extraction and solvent removal, the extract contains organic matter derived from rapeseed meal, with a dry matter content close to 100% .

The resulting complex contains a specific lipid and volatile fraction including ceramides, C8 C24 fatty amides, tocopherols and polyphenols.

This makes ViroBiome™ CERA a relevant botanical module for lipid barrier reinforcement, skin comfort and microbiome compatible surface balance.

Scientific & Functional Foundation

Lipid Barrier Reinforcement

The skin barrier depends on lipid cohesion, hydrolipidic film integrity and organized intercellular lipids.

ViroBiome™ CERA is designed to support:

• lipid cohesion
• barrier stability
• hydration maintenance
• surface comfort
• resilience after friction and exposure

The safest public positioning is “lipid barrier reinforcement” and “surface resilience support”, not therapeutic repair.

Rapeseed Ceramides Together With Their Associated Membrane Phospholipids

ViroBiome™ CERA should be presented as a biomimetic lipid complex based on rapeseed ceramides together with their associated membrane phospholipids.

This wording supports a stronger biological interface narrative.

Recommended formulation:

"ViroBiome™ CERA contains rapeseed ceramides together with their associated membrane phospholipids, designed to support lipid cohesion, surface comfort and barrier resilience."

For regulatory prudence, avoid implying that the complex fully reconstructs human skin lipids unless this has been specifically validated in finished formulations.

Ceramides & C8 C24 Fatty Amides

The patent describes a rapeseed meal extract comprising compounds selected from ceramides and C8 C24 fatty amides.

This supports a biomimetic lipid positioning because these lipid structures are directly relevant to surface organization, comfort and barrier balance.

Tocopherols & Polyphenols

The patent describes the presence of gamma tocopherols, alpha tocopherols and polyphenols in the extract.

The extract may contain polyphenols ranging from 100 to 150 ppm, preferably 135 ppm . The patent also reports alpha tocopherol and gamma tocopherol fractions in the extract .

These elements support an environmental stress positioning, particularly for pollution exposed, UV exposed and climate stressed biological interfaces.

Non Therapeutic Cosmetic Positioning

The patent describes the compositions as non therapeutic cosmetic or food compositions, intended for application to healthy skin .

Therefore, the safest public positioning is:

• cosmetic
• hygiene adjacent
• non systemic
• microbiome compatible
• barrier oriented
• functional surface support

Core Functional Benefits

Lipid Barrier Reinforcement

Supports lipid cohesion and barrier integrity in exposed or aging sensitive surfaces.

Hydration & Comfort Support

Helps maintain a more comfortable surface environment by supporting the lipid phase of the barrier.

Environmental Stress Resilience

Supports exposed interfaces facing pollution, heat, UV related stress and urban environmental pressure.

Microbiome Compatible Balance

Designed to support surface balance without broad biocidal positioning.

Plant Derived Circular Innovation

Valorizes rapeseed meal, a plant based by product, into a high value functional lipid complex.

Longer Contact Compatibility

More suitable than ViroBiome™ Pepti for longer contact hygiene, skin comfort and nonwoven applications, subject to final formulation and safety validation.

Industrial & Formulation Integration

Technology format

Stabilized lipophilic concentrate

Indicative inclusion level

2.5% in final formulation, to be adapted according to product category, regulatory pathway, exposure duration and tolerance assessment.

Compatible formats

• creams
• emulsions
• serums
• lotions
• barrier care formulations
• intimate dermal applications
• treated wipes
• tissues
• functional nonwovens
• absorbent hygiene materials
• bioactive coatings
• multilayer hygiene substrates

The patent indicates that cosmetic compositions may contain the extract at levels ranging from 0.001% to 30% by weight, preferably from 0.1% to 20% by weight relative to the total composition .

For ViroBiome industrial positioning, 2.5% remains a reasonable indicative level for B2B formulation screening, subject to final tolerance and performance validation.

Priority Application Segments

Functional Nonwovens

Lipid based comfort layer for next generation hygiene materials.

Wipes & Tissues

Surface comfort, repeated contact support and microbiome compatible barrier reinforcement.

Feminine Hygiene

Lipid barrier support for sensitive biological interfaces.

Incontinence Care

Comfort and barrier resilience for aging sensitive skin exposed to repeated humidity, friction and cleansing.

Baby Care

Soft lipid barrier support for fragile skin, subject to dedicated safety and tolerance validation.

Intimate Care

Surface comfort and microbiome compatible balance for sensitive areas.

Beauty & Aging Sensitive Skin

Lipid support for barrier fragility, dryness and environmental stress exposure.

Urban & Climate Stress Care

Barrier resilience for skin exposed to pollution, heat, dehydration pressure and seasonal allergens.

Platform Synergy

ViroBiome™ CERA alone

Plant derived lipid barrier reinforcement and microbiome compatible surface comfort.

ViroBiome™ CERA + ViroBiome™ Safety

Forms ViroBiome™ SHIELD.

This module combines functional surface protection with lipid barrier reinforcement.

Positioning:

• exposed interface resilience
• lipid barrier support
• microbiome compatible comfort
• longer contact hygiene and nonwoven applications

ViroBiome™ CERA + ViroBiome™ Pepti

Possible in controlled formats only.

Because Peptides de colza should be reserved for rinse off or short contact applications, any CERA + Pepti combination must be positioned for controlled exposure, not prolonged dermal or mucosal contact.

Advanced Surface Architecture

ViroBiome™ CERA can be integrated into compartmentalized surface architectures designed to support localized lipid deposition, controlled migration and enhanced retention on exposed biological interfaces.

These architectures may support:

• lipid comfort layer
• protective top layer
• controlled deposition layer
• bioactive reservoir layer
• nonwoven support substrate
• differentiated release between comfort and protection phases
• compatibility with multilayer hygiene materials

This makes CERA particularly relevant for nonwovens, wipes, tissues, absorbent hygiene and skin contact materials where comfort, barrier support and surface resilience are central.

Strategic Positioning

Conventional Skincare

Hydrate.

Conventional Hygiene

Clean. Remove. Eliminate.

Next Generation Augmented Hygiene

Rebuild. Reinforce. Preserve.

ViroBiome™ CERA is positioned as a plant derived structural lipid module supporting barrier resilience in urbanized, aging and climate stressed societies.

It is not a pharmaceutical active.

It is not a biocide.

It is not an antimicrobial technology.

It is a lipid barrier reinforcement and microbiome compatible comfort module for advanced hygiene, dermal care and functional nonwoven systems.

Scientific & IP Access

Detailed scientific documentation, formulation guidance, experimental data and intellectual property files are available under confidentiality agreement.

Contact
dominique.delarche@virobiome.com