ViroBiome Safety

ViroBiome™ Safety

Plant-Based Furin Inhibitor – Instant Viral Deactivation, Microbiome-Safe

What is ViroBiome™ Safety?

ViroBiome™ Safety is a patented, concentrated bioactive complex based on α- and β-amyrins (pentacyclic triterpenes) derived from Protium heptaphyllum. It acts as a natural, non-proteinic furin inhibitor, capable of bioactively deactivating up to 99.3% of viruses in under 30 seconds, while preserving the skin and mucosal microbiome.

Patent EP21719616 – A novel non-proteinic furin inhibitor

Key Features

Furin inhibition: blocks activation of viral glycoproteins, preventing cell entry and infection

Ultra-fast action: proven efficacy on SARS-CoV-2 (−98% infectivity at 0.25% in minutes)

Microbiome-safe: does not disturb beneficial cutaneous or mucosal flora

Broad-spectrum antiviral:

• • HIV, HPV, HSV, SARS-CoV-2, Zika, Dengue, Chikungunya, Ebola, Marburg...

  • Bacterial toxins: diphtheria, anthrax

  • Inhibits pro-oncogenic pathways (TGFβ, MMPs)

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Industrial Applications & Usage

• Form: lipophilic standardized concentrate (AMY complex)

• Recommended dosage: 2.5% dilution in final formulations

• Compatible with: sprays, creams, gels, wipes, serums, medical coatings

Industrial sprayability

• Can be sprayed directly on surfaces, fabrics, or devices

• 1 mL = 400 cm² protected surface

• Suitable for automated integration into:

  • Intimate protection (wipes, pads, liners, underwear)

  • Medical devices (masks, gloves, probes, dressings — disposable or reusable)

  • Reusable or single-use fabrics treated for viral deactivation

Waste Management Benefits

Surfaces treated with ViroBiome™ Safety are no longer infectious
Facilitates safer and lower-cost disposal of used PPE or hygiene materials
Supports biohazard reduction and on-site viral neutralization

ViroBiome Combinatory Potential

Combination

Resulting Solution

Functional Synergy

Safety + Pepti

ViroBiome™ PROTECT

Antiviral + ACE2-blocking peptides → immunity + repair

Safety + Cera

ViroBiome™ SHIELD

Antiviral + ceramides → barrier repair + hydration

Origin & Sustainability

• 100% plant-based – no proteins or toxic solvents

• Extracted from Protium heptaphyllum resins or biotech-derived α-/β-amyrins

• Non-toxic, biodegradable, safe for skin and environment

For Industrial Integration

We offer:

• Bulk supply of ready-to-dilute concentrate (2.5%)

• Full formulation support (cosmetic, hygiene, medical, textile)

• Scientific dossiers, in vitro data, and patent support

• Co-development for next-gen antiviral products

Furin Inhibitor : Biological Testing

Anti-infective efficacy test against SARS-CoV-2 coronavirus.

The Virostatic HTRE Spray reduced SARS-CoV-2 pseudovirus cell entry by up to ~98%, demonstrating strong anti-infective efficacy. 

 Inhibition assay against recombinant human furin enzyme.

The Virostatic HTRE Spray strongly inhibits recombinant human furin activity, blocking a key viral activation mechanism. 

  Proven skin tolerance

Dermatological test on 10 volunteers with sensitive skin: 0 reaction, classified as "non-irritant" (CGDA report, 2021)

  Validated nasal tolerance

21-day clinical study under ENT supervision: well tolerated, no serious adverse events (CGDA report, 2021)

  Ex vivo barrier activity

HTR1 resin reduces IL-6 inflammatory response by up to 47% when exposed to irritant particles

  Confirmed mucosal tolerance in vivo (rats)

No adverse effects after 15 repeated nasal administrations (ISO 10993-10 & 23 standards)

  Non-cytotoxic and non-permeating

Ex vivo and in vivo tests conducted in compliance with ISO 10993 standards

  Surface-level action only, no tissue penetration

Protective film-forming effect demonstrated on human skin explants

Access to the test results is subject to prior discussion and the signing of a non-disclosure agreement (NDA).